Liver Immunology

The human liver is usually perceived as a non-immunological organ engaged primarily in metabolic, nutrient storage and detoxification activities. The healthy liver is also a site of complex immunological activity mediated by a diverse immune cell repertoire as well as non-hematopoietic cell populations. In the non-diseased liver, metabolic and tissue remodeling functions require elements of inflammation. In this complex microenvironment, the hepatic immune system tolerates harmless molecules while at the same time remaining alert to possible infectious agents, malignant cells or tissue damage.

In the healthy liver, constantly changing metabolic and tissue remodeling activity, combined with regular exposure to microbial products, results in persistent, regulated inflammation. These inflammatory processes act in a tightly controlled fashion and are stimulated to additional activity only when the liver is required to rid itself of hepatotropic pathogens, malignant cells or toxic products of metabolic activity. Failure to clear such dangerous stimuli and resolve inflammation, leads to chronic infection, autoimmunity or tumor growth. This is inevitably associated with chronic pathological inflammation and disrupted tissue homeostasis, which can progress to fibrosis, cirrhosis and liver failure.

  • Liver Immune Tolerance
  • Hepatic Innate Immunity
  • Liver Sinusoidal Endothelial Cells
  • Liver as an¬†Immunological Organ

Related Conference of Liver Immunology

December 17-18, 2018

3rd World Liver Congress

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16th World Congress on Gastroenterology & Therapeutics

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World Congress on Pancreatic Cancer and Liver Diseases

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20th World Congress on Gastroenterology

Berlin, Germany
April 24-25, 2019

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May 15-16, 2019

21st World Congress on Advances in Gastroenterology and Hepatology

Mercure Melbourne Albert Park, Melbourne, Australia
July 08-09, 2019

14th Euro-Global Gastroenterology Conference

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July 15-16, 2019

7th International Conference on Hepatology

Sydney, Australia
September 23-24, 2019

World Summit on Liver Cirrhosis and Hepatitis

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19th World Gastroenterologists Summit

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Liver Immunology Conference Speakers

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