Hepato-biliary diseases

Hepatobiliary diseases are diseases that affect the biliary tract or the liver. Cholangiocarcinoma is usually a bile duct that presents a malignant tumor. Treating the disease requires removal and/or resection. Biliary structures (both malignant and benign) – occur when the bile ducts become inflamed or injured. The ducts narrow and form a stricture. They are often caused by injury or cancer. Bile duct stones – are stones that occur within the bile duct, similar to a gallstone. They often start developing in the gallbladder and make their way into the bile duct. The hepatobiliary system is made up of the liver, gall bladder and bile ducts. Conditions or diseases that cause harm to these areas, which can be life threatening, are referred to as hepatobiliary diseases.

Caroli disease and Caroli syndrome are rare congenital disorders of the intrahepatic bile ducts. They are both characterized by dilatation of the intrahepatic biliary tree. The term Caroli disease is applied if the disease is limited to ectasia or segmental dilatation of the larger intrahepatic ducts. Biliary atresia is a rare disease of the liver and bile ducts that occurs in infants. Neonatal hemochromatosis is a syndrome in which severe liver disease of fetal or perinatal onset is associated with deposition of stainable iron in extrahepatic sites. Survival rates in babies who undergo liver transplantation are reportedly 50%.

  • Acute liver failure
  • Biliary atresia
  • Pediatric Caroli disease
  • Cholangiocarcinoma¬†(biliary tree cancer)
  • Primary Neonatal Hemochromatosis

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