Autoimmune liver diseases

When the immune system of the body targets the liver, it can result in inflammation and autoimmune liver diseases. If the liver inflammation is not addressed, it could eventually result in cirrhosis, which could cause liver cancer and liver failure.

The three most prevalent autoimmune liver illnesses are autoimmune hepatitis, primary biliary cholangitis, and primary sclerosing cholangitis, despite the fact that a variety of autoimmune ailments can affect the liver. These ailments can manifest alone or as a component of "overlap" illnesses.

Autoimmune hepatitis (AIH) which can cause cirrhosis and abrupt liver failure, can afflict both adults and children. Prior to liver failure, it is frequently asymptomatic and without any symptoms. Additionally, it may also be accompanied by general symptoms like weariness, nauseousness, abdominal discomfort, or joint pain.

Primary biliary cholangitis (PBC) is a condition where the liver's biliary ducts are destroyed by the body's immune system, making it difficult for the liver to discharge bile. More frequently than men, it affects women. It cannot show any symptoms at all or it might show symptoms like weariness, itchiness, dry lips, dry eyes, elevated cholesterol, or bone damage. It could develop together with other autoimmune diseases. PBC can cause cirrhosis and liver failure if it is not addressed.                                                                                                                                                                                                                                              Primary sclerosing cholangitis (PSC) Inflammation and scarring of the bile ducts are characteristics of primary sclerosing cholangitis (PSC), which can make it difficult for bile to pass through. It may be asymptomatic, like other autoimmune liver illnesses, or it may be accompanied by symptoms like itching or jaundice. PSC can have an impact on both kids and adults. Occurs when the biliary ducts within the liver are destroyed by the body’s own immune cells, impairing the liver’s ability to excrete bile. It affects women more often the men. It may be asymptomatic or may be associated with symptoms such as fatigue, itching, dry mouth, dry eyes, high cholesterol or bone disease. It may occur in association with other autoimmune conditions. If left untreated, PBC can lead to cirrhosis and liver failure.

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